The effect of the resources-based learning model in ecosystem learning to improve student learning outcomes

This study aims to determine the effect of the Resource Based Learning (RBL) model in Ecosystem learning and its effect on biology learning outcomes at SMAN 3 Mataram. This type of research is research using a quantitative approach. The sample of this research was the students of class IX of SMAN 3 Mataram, which amounted to 32 students of X MIPA 1 for the control class and 32 students of X iMIPA i2 for the experimental class. The research data was obtained from a questionnaire on implementing the lesson plan and a learning outcome (post-test score) on ecosystem materials. The data analysis results show that the questionnaire score interval level for implementing the Resource Based Learning (RBL) model is 100% (very high). The conventional model shows the score interval that is implemented is 87.5%, and that is not implemented is 12.5%, and the level of validity of the questions in the cognitive domain, including the very valid criteria and the level of reliability of the questions in the cognitive domain, the criteria for reliable. The results of the data analysis of learning outcomes showed differences in the average post-test scores between the experimental class through the application of learning using the resource-based learning (RBL) learning model and the control class through the application of the conventional learning model. The post-test mean in the experimental class was 91.36, while the post-test mean in the control class was 71.69. The significance value of the count sample obtained is 0.532, the significance value obtained is greater than 0.05 Ho is rejected, and H1 is accepted, which means that the use of the Resource-based Learning (RBL) learning model is effective on student biology learning outcomes at SMAN 3 Mataram

Pengelolaan Pembiayaan Pendidikan Melalui Bantuan Operasional Sekolah Pada Min Cempala Kuneng Kabupaten Pidie

: State Government Elementary School Cempala Kuneng is an educational institution that serves as a base level finance management education research and discussion of the results of this study, the management of the financing of education at the Min Cempala Kuneng have been implemented as programmed. This study used a descriptive approach and qualitative methods of data collection techniques documentation, observations and interviews, the research subject chief Madrasah, committee, treasurer, operator / administrative staff and teachers councils in Cempala Kuneng MIN. This study shows that: 1) planning on BOS MIN Cempala Kuneng already accordance with prevailing regulations. implementation is transparent and used in accordance with the existing guidelines, previously held a meeting with the school committee and the board of teachers. 2) Financing on BOS MIN Cempala Kuneng guided by the guide book for the procurement of BOS is the subject of books, teacher training, purchase of consumables, implement student activities, for transport costs, procurement of laboratory supplies, documentation, maintenance costs and the cost of making and lightweight procurement report. 3) Monitoring of the implementation of BOS MIN Cempala Kuneng made superintendent of schools and education authorities who are monitoring the implementation of government\u27s efforts mesikpun indirectly but very helpful in preventing the abuse of authority and misconduct. 4). BOS funds MIN Cempala Kuneng very supportive school students to free tuition, support schools in implementing the program activities, either to improve the infrastructure and improve the competence of teachers and educators

Prediction of far-field acoustic emissions from cavitation clouds during shock wave lithotripsy for development of a clinical device

This study presents the key simulation and decision stage of a multi-disciplinary project to develop a hospital device for monitoring the effectiveness of kidney stone fragmentation by shock wave lithotripsy (SWL). The device analyses, in real time, the pressure fields detected by sensors placed on the patient's torso, fields generated by the interaction of the incident shock wave, cavitation, kidney stone and soft tissue. Earlier free-Lagrange simulations of those interactions were restricted (by limited computational resources) to computational domains within a few centimetres of the stone. Later studies estimated the far-field pressures generated when those interactions involved only single bubbles. This study extends the free-Lagrange method to quantify the bubble–bubble interaction as a function of their separation. This, in turn, allowed identification of the validity of using a model of non-interacting bubbles to obtain estimations of the far-field pressures from 1000 bubbles distributed within the focus of the SWL field. Up to this point in the multi-disciplinary project, the design of the clinical device had been led by the simulations. This study records the decision point when the project's direction had to be led by far more costly clinical trials instead of the relatively inexpensive simulations. <br/

Pelaksanaan Supervisi Klinis Di SMA Negeri 1 Kuala Kecamatan Kuala Kabupaten Nagan Raya

Supervisi klinis merupakan bagian dari supervisi pengajaran, yaitu supervisi yang difokuskan pada perbaikan pembelajaran melalui siklus yang sistematis mulai dari tahap perencanaan, pengamatan dan analisis yang intensif. Tujuan penelitian ini adalah untuk mendapatkan gambaran dan informasi mengenai program, prinsip dan mekanisme supervisi klinis yang dilaksanakan oleh kepala sekolah. Penelitian ini menggunakan metode deskriptif dengan pendekatan analisis kualitatif. Teknik pengumpulan data dilakukan melalui wawancara, observasi dan studi dokumentasi. Subjek penelitian adalah Kepala sekolah, wakil kepala sekolah, MGMP dan guru yang ada pada SMA Negeri 1 Kuala, kecamatan Kuala kabupaten Nagan Raya. Hasil penelitian menunjukkan bahwa kepala sekolah di SMA Negeri 1 Kuala, telah melaksanakan program supervisi klinis, sebelum melaksanakan program supervisi klinis, kepala sekolah dengan melibatkan wakil kepala sekolah, ketua MGMP dan guru senior menyusun program kegiatan supervisi klinis, membuat jadwal kegiatan, mengadakan kunjungan kelas, menginventarisir temuan supervisi dan menyusun laporan pelaksanaan supervisi klinis. Prinsip supervisi klinis yang dijalankan oleh kepala sekolah bersifat konstruktif, menolong guru agar senantiasa tumbuh sendiri tidak tergantung pada supervisor, supervisi harus realistis dan didasarkan pada kenyataan yang sebenarnya. Mekanisme supervisi klinis yang dijalankan oleh kepala sekolah SMA Negeri 1 Kuala kecamatan Kuala kabupaten Nagan Raya yaitu pertemuan awal, observasi dan pertemuan akhir. Hasil dari pelaksanaan supervisi klinis yang dijalankan oleh kepala sekolah akan di sampaikan ke supervisor tingkat kecamatan dan disampaikan ke dinas pendidikan

PEGylated Domain I of Beta-2-Glycoprotein I Inhibits the Binding, Coagulopathic, and Thrombogenic Properties of IgG From Patients With the Antiphospholipid Syndrome

APS is an autoimmune disease in which antiphospholipid antibodies (aPL) cause vascular thrombosis and pregnancy morbidity. In patients with APS, aPL exert pathogenic actions by binding serum beta-2-glycoprotein I (β2GPI) via its N-terminal domain I (DI). We previously showed that bacterially-expressed recombinant DI inhibits biological actions of IgG derived from serum of patients with APS (APS-IgG). DI is too small (7 kDa) to be a viable therapeutic agent. Addition of polyethylene glycol (PEGylation) to small molecules enhances the serum half-life, reduces proteolytic targeting and can decrease immunogenicity. It is a common method of tailoring pharmacokinetic parameters and has been used in the production of many therapies in the clinic. However, PEGylation of molecules may reduce their biological activity, and the size of the PEG group can alter the balance between activity and half-life extension. Here we achieve production of site-specific PEGylation of recombinant DI (PEG-DI) and describe the activities in vitro and in vivo of three variants with different size PEG groups. All variants were able to inhibit APS-IgG from: binding to whole β2GPI in ELISA, altering the clotting properties of human plasma and promoting thrombosis and tissue factor expression in mice. These findings provide an important step on the path to developing DI into a first-in-class therapeutic in APS

Electronic hand hygiene quality and duration monitoring in pre-school children: a feasibility study

Background: Hand hygiene is regarded as the most important measure to prevent spread of infectious diseases. The aim of this study was to assess the feasibility of a prototype application in an electronic device in educating, stimulating and monitoring hand hygiene quality in young children. Method: A pre-school was provided with an interactive hand hygiene application for two months. The device features an online administrator dashboard for data collection and for monitoring the children's hand washing steps and duration. A good hand washing is defined as hand washing which comprise all of the steps outlined in the World Health Organization (WHO) guidelines. Results: The prototype managed to capture 6882 hand wash performed with an average of 20.85 seconds per hand wash. Washing hands palm to palm was the most frequent (79.9%) step performed, whereas scrubbing fingernails and wrists were the least (56%) steps performed. Conclusions: The device is a good prototype to educate, stimulate and monitor good hand hygiene practices. However, other measures should be undertaken to ensure sustainability of the practices

Healthy hands: development and evaluation of a knowledge transfer program

Introduction: Children in pre-schools are at high risk of getting infections due to overcrowding, minimal awareness of basic hygiene and lack of immunity against microorganisms. Hand hygiene practice should be started at home where parents set good example, followed by formal education in pre-schools, primary and secondary school. This study aimed to develop a comprehensive program on hand hygiene practice in pre-schools. This paper presents the developmental aspects of the program material and the results of its evaluation process in a selected pre-school. Methods: Stage of development involved preparation of song, lyric, video clip, infographic and tablet application. The module was introduced during an intervention day called ‘Healthy Hands’ day. The acceptance of the module was evaluated before and after the intervention day. Evaluation was done by assessing pre-school children by face-to-face interview about knowledge on hand hygiene techniques and routine, such as before or after certain activities. Results: We managed to compose a song in three languages (Malay, English & Arabic), produced a video clip, an infographic and tablet application. A total of 227 children participated. Post intervention evaluation showed significant (p<0.001) increase of knowledge for eight out of eleven handwashing steps. The knowledge on hand hygiene routine i.e. after toilet, after playing outdoor, after sneezing and after playing with pet was also increased significantly. Conclusion: This comprehensive knowledge transfer program significantly improved the children’s hand hygiene techniques and routine and is recommended to be integrated into pre-school curriculum

Human Metapneumovirus Inhibits IFN-β Signaling by Downregulating Jak1 and Tyk2 Cellular Levels

Human metapneumovirus (hMPV), a leading cause of respiratory tract infections in infants, inhibits type I interferon (IFN) signaling by an unidentified mechanism. In this study, we showed that infection of airway epithelial cells with hMPV decreased cellular level of Janus tyrosine kinase (Jak1) and tyrosine kinase 2 (Tyk2), due to enhanced proteosomal degradation and reduced gene transcription. In addition, hMPV infection also reduced the surface expression of type I IFN receptor (IFNAR). These inhibitory mechanisms are different from the ones employed by respiratory syncytial virus (RSV), which does not affect Jak1, Tyk2 or IFNAR expression, but degrades downstream signal transducer and activator of transcription proteins 2 (STAT2), although both viruses are pneumoviruses belonging to the Paramyxoviridae family. Our study identifies a novel mechanism by which hMPV inhibits STAT1 and 2 activation, ultimately leading to viral evasion of host IFN responses

Urban coral reefs: Degradation and resilience of hard coral assemblages in coastal cities of East and Southeast Asia

© 2018 The Author(s) Given predicted increases in urbanization in tropical and subtropical regions, understanding the processes shaping urban coral reefs may be essential for anticipating future conservation challenges. We used a case study approach to identify unifying patterns of urban coral reefs and clarify the effects of urbanization on hard coral assemblages. Data were compiled from 11 cities throughout East and Southeast Asia, with particular focus on Singapore, Jakarta, Hong Kong, and Naha (Okinawa). Our review highlights several key characteristics of urban coral reefs, including “reef compression” (a decline in bathymetric range with increasing turbidity and decreasing water clarity over time and relative to shore), dominance by domed coral growth forms and low reef complexity, variable city-specific inshore-offshore gradients, early declines in coral cover with recent fluctuating periods of acute impacts and rapid recovery, and colonization of urban infrastructure by hard corals. We present hypotheses for urban reef community dynamics and discuss potential of ecological engineering for corals in urban areas